SCHEMBL29367687

SCHEMBL29367687

CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACE P12821 4/20 0.77
CTSL P07711 2/20 0.76
CTSS P25774 1/20 0.76
CTSK P43235 1/20 0.76
SCN9A Q15858 1/20 0.70
TACR1 P25103 2/20 0.70
MAPT P10636 2/20 0.68
TP53 P04637 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.66
ALOX15 P16050 1/20 0.66
SSTR3 P32745 1/20 0.63
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
ITGB2 P05107 1/20 0.62
ICAM1 P05362 1/20 0.62
ITGAL P20701 1/20 0.62
ECE1 P42892 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1003555 1.00 ACE (0.77) ACECTSLCTSSCTSKSCN9A
SCHEMBL850438 1.00 ACE (0.77) ACECTSLCTSSCTSKSCN9A
SCHEMBL1486167 1.00 ACE (0.77) ACECTSLCTSSCTSKSCN9A
SCHEMBL30976323 1.00 ACE (0.77) ACECTSLCTSSCTSKSCN9A
Hydrochloric Acid SCHEMBL31472643 0.99 ACE (0.75) ACECTSLCTSSCTSKSCN9A
SCHEMBL30699849 0.99 ACE (0.75) ACECTSLCTSSCTSKSCN9A
Fluoride SCHEMBL7445962 0.99 ACE (0.75) ACECTSLCTSSCTSKSCN9A
Fluoride SCHEMBL7445954 0.99 ACE (0.75) ACECTSLCTSSCTSKSCN9A
SCHEMBL11403615 0.96 ACE (0.84) ACECTSLCTSSCTSKSCN9A
SCHEMBL27871524 0.96 CTSL (0.76) ACECTSLCTSSCTSKSCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843638-A Preparation and application of bifunctional molecular compound based on RSL3 induced GPX4 protein degradation 沈阳药科大学 2024-04-09 CN claimed
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN claimed
CN-113773295-B Synthesis method of monosubstituted dihydro chromone and application of monosubstituted dihydro chromone in treatment of pulmonary inflammation such as COPD (chronic disease) 广东省科学院动物研究所 2023-06-20 CN claimed
CN-109432394-B Octreotide acetate injection pharmaceutical composition and application thereof 成都天台山制药有限公司 2022-02-01 CN claimed
EP-4698551-A1 NOVEL SMALL MOLECULE AGONISTS OF INSULIN RECEPTOR (INSR) AS ANTI-DIABETES DRUGS The University of Hong Kong (CN) 2026-02-25 EP disclosed
CN-120647651-B Beta-carboline-thiazole compound, preparation method thereof and application thereof as drug resistance reversal agent 烟台大学 2025-11-07 CN disclosed
CN-120647651-A Beta-carboline-thiazole compound, preparation method thereof and application thereof as drug resistance reversal agent 烟台大学 2025-09-16 CN disclosed
WO-2025090774-A1 CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE SEAGEN INC. (US) 2025-05-01 WO disclosed
WO-2024217497-A1 NOVEL SMALL MOLECULE AGONISTS OF INSULIN RECEPTOR (INSR) AS ANTI-DIABETES DRUGS THE UNIVERSITY OF HONG KONG (CN) 2024-10-24 WO disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
EP-4034105-B1 POLYMORPH FORM OF (R)-2-[2-AMINO-3-(INDOL-3-YL)PROPIONYLAMINO]-2-METHYLPROPIONIC ACID AND USES THEREOF GALIMEDIX THERAPEUTICS INC (US) 2024-07-31 EP disclosed
CN-114805305-B Compound and application thereof 成都诺和晟泰生物科技有限公司 2024-04-26 CN disclosed
CN-114805305-A Compound and application thereof 成都诺和晟泰生物科技有限公司 2022-07-29 CN disclosed
EP-4031557-A1 METHODS FOR PRODUCING D-TRYPTOPHAN AND SUBSTITUTED D-TRYPTOPHANS The Regents of the University of California (US) 2022-07-27 EP disclosed
CN-114786697-A Diterpenoids acting on Protein Kinase C (PKC) K-GEN股份有限公司 2022-07-22 CN disclosed
US-20220220155-A1 VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2022-07-14 US disclosed
CN-114466652-A Novel polymorphic crystal forms of (R) -2- [ 2-amino-3- (indol-3-yl) propionylamino ] -2-methylpropionic acid and uses thereof 加利梅迪克斯治疗公司 2022-05-10 CN disclosed
EP-3966234-A1 VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF Consejo Superior De Investigaciones Científicas (ES) 2022-03-16 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
CN-109432394-B Octreotide acetate injection pharmaceutical composition and application thereof 成都天台山制药有限公司 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220220155-A1 VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF LDLR, APOB, HDLBP ACE 1604/4885CTSL 2454/4885CTSS 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.