Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17559145 | 0.78 | KDM4E (0.59) | KDM5AKDM4CPARP1ALOX5KDM4E | |
| SCHEMBL10484937 | 0.78 | GLS (0.62) | ALDH1A1GLSALOX5KDM4E | |
| SCHEMBL17559148 | 0.71 | KDM4E (0.59) | KDM5AKDM4CPARP1ALOX5KDM4E | |
| SCHEMBL28960848 | 0.71 | PARP1 (0.40) | ALDH1A1GLSPARP1KDM4E | |
| SCHEMBL30976328 | 0.71 | MPO (0.44) | ALDH1A1DAOGLSKDM4E | |
| SCHEMBL11388064 | 0.68 | METAP2 (0.41) | ALDH1A1KDM4EADORA1 | |
| SCHEMBL15680182 | 0.68 | SRC (0.49) | ALDH1A1DAOGLSKDM4E | |
| SCHEMBL30976381 | 0.68 | MPO (0.44) | ALDH1A1DAOGLSKDM4E | |
| SCHEMBL29900257 | 0.68 | PARP1 (0.44) | ALDH1A1GLSPARP1KDM4E | |
| SCHEMBL28960486 | 0.67 | MEN1 (0.46) | DAOPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |