Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | DTYMK | P23919 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976347 | 0.85 | MEN1 (0.69) | L3MBTL1ALDH1A1DTYMKTSHRLMNA | |
| SCHEMBL30976354 | 0.80 | ALDH1A1 (0.58) | L3MBTL1KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL23966843 | 0.75 | ALOX15 (0.51) | DTYMKLMNAHTTCHRM2CHRM4 | |
| SCHEMBL13720683 | 0.74 | LMNA (0.41) | ALDH1A1DTYMKTSHRLMNAMEN1 | |
| SCHEMBL30976411 | 0.74 | TP53 (0.56) | L3MBTL1KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL30976334 | 0.74 | POLB (0.54) | L3MBTL1ALDH1A1DTYMKLMNAMEN1 | |
| SCHEMBL31199177 | 0.74 | ALDH1A1 (0.59) | L3MBTL1KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL30976476 | 0.72 | MEN1 (0.51) | L3MBTL1ALDH1A1DTYMKLMNAMEN1 | |
| SCHEMBL30976251 | 0.72 | MEN1 (0.51) | L3MBTL1ALDH1A1DTYMKLMNAMEN1 | |
| SCHEMBL30976241 | 0.72 | MEN1 (0.50) | L3MBTL1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |