Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | GRK5 | P34947 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246346 | 1.00 | GABRA1 (0.44) | GABRA1GABRB1GABRA3GABRB2JAK2 | |
| SCHEMBL29246687 | 0.86 | KMT2A (0.45) | GABRA1GABRA3MEN1KMT2AHCRTR1 | |
| SCHEMBL29246342 | 0.82 | KDM4E (0.46) | GABRA1GABRB1GABRA3GABRB2MEN1 | |
| SCHEMBL3011731 | 0.75 | ALDH1A1 (0.69) | GABRA1GABRB1GABRA3GABRB2MEN1 | |
| SCHEMBL2327495 | 0.73 | GABRA1 (0.50) | GABRA1GABRB1GABRA3GABRB2JAK2 | |
| SCHEMBL10067389 | 0.72 | LMNA (0.49) | JAK2PAK4NTRK1CSF1RRET | |
| SCHEMBL29246343 | 0.72 | KDM4E (0.55) | MEN1KMT2AHCRTR1RAB9AHPGD | |
| SCHEMBL26963026 | 0.72 | ALDH1A1 (0.41) | GABRA1GABRB1GABRA3GABRB2MEN1 | |
| SCHEMBL2471778 | 0.72 | ALDH1A1 (0.41) | GABRA1GABRB1GABRA3GABRB2MEN1 | |
| SCHEMBL31145891 | 0.71 | KMT2A (0.43) | GSK3BMEN1KMT2AHCRTR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307461-A | Preparation method of light-induced palladium-catalyzed difluoro methylene indole compound | 大连理工大学 | 2024-07-09 | — | — | CN | disclosed |