Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246346 | 0.86 | GABRA1 (0.44) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL30978355 | 0.86 | GABRA1 (0.44) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL31145891 | 0.84 | KMT2A (0.43) | KMT2AMEN1HCRTR1MAPTSMN1; SMN2 | |
| SCHEMBL29246342 | 0.83 | KDM4E (0.46) | KMT2AMEN1HCRTR1MAPTSMN1; SMN2 | |
| Butyric Acid SCHEMBL27760604 | 0.77 | MEN1 (0.48) | KMT2AMEN1NPC1RAB9AKEAP1 | |
| SCHEMBL28819184 | 0.76 | SIRT1 (0.48) | KMT2AMEN1HCRTR1MAPTSMN1; SMN2 | |
| SCHEMBL3283431 | 0.76 | ALDH1A1 (0.69) | KMT2AMEN1HCRTR1MAPTSMN1; SMN2 | |
| SCHEMBL10067361 | 0.73 | KMT2A (0.50) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29246343 | 0.72 | KDM4E (0.55) | KMT2AMEN1HCRTR1MAPTSMN1; SMN2 | |
| SCHEMBL7651932 | 0.72 | FEN1 (0.51) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307461-A | Preparation method of light-induced palladium-catalyzed difluoro methylene indole compound | 大连理工大学 | 2024-07-09 | — | — | CN | disclosed |