SCHEMBL30978366

SCHEMBL30978366

O=C(O)c1ccc(-c2ccc(C(=O)O)cc2[N+](=O)[O-])nc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.57
P4HA1 P13674 2/20 0.54
P4HTM Q9NXG6 1/20 0.54
TSHR P16473 2/20 0.53
LMNA P02545 1/20 0.53
ALDH1A1 P00352 1/20 0.49
APEX1 P27695 1/20 0.49
HCAR3 P49019 8/20 0.49
LDHA P00338 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30978367 0.83 ALDH1A1 (0.60) CASP6TSHRLMNAALDH1A1HCAR3
SCHEMBL11761567 0.83 ALDH1A1 (0.60) CASP6TSHRLMNAALDH1A1HCAR3
SCHEMBL11195885 0.82 CASP6 (0.75) CASP6TSHRLMNAAPEX1HCAR3
SCHEMBL31548567 0.78 CASP6 (0.64) CASP6TSHRLMNAALDH1A1APEX1
SCHEMBL17197945 0.78 CASP6 (0.68) CASP6TSHRLMNAAPEX1HCAR3
SCHEMBL8700703 0.77 CASP6 (0.54) CASP6TSHRLMNAAPEX1HCAR3
SCHEMBL9557826 0.76 CASP6 (0.66) CASP6TSHRLMNAAPEX1HCAR3
SCHEMBL23499234 0.75 CASP6 (0.64) CASP6TSHRLMNAAPEX1HCAR3
SCHEMBL30978369 0.75 P4HA1 (0.61) P4HA1P4HTMALDH1A1HCAR3LDHA
SCHEMBL15062366 0.75 CASP6 (0.64) CASP6TSHRLMNAALDH1A1HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164905-A 2- (Pyridine-2-yl) aniline compound and synthesis method thereof 南京大学 2024-06-11 CN disclosed