SCHEMBL309808

SCHEMBL309808

CCOC(=O)c1c[nH]nc1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
HSD17B10 Q99714 2/20 0.50
TSHR P16473 1/20 0.48
KDM4E B2RXH2 6/20 0.47
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
RECQL P46063 1/20 0.46
GAA P10253 1/20 0.45
MAPK1 P28482 1/20 0.45
MAPT P10636 2/20 0.44
LMNA P02545 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
TP53 P04637 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAOA P21397 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Aminopyridine SCHEMBL7210909 0.85 RAB9A (0.49) ALDH1A1MEN1KMT2AHSD17B10TSHR
SCHEMBL263628 0.81 TSHR (0.52) ALDH1A1MEN1KMT2AHSD17B10TSHR
SCHEMBL1192752 0.80 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AHSD17B10TSHR
SCHEMBL3376695 0.80 KDM4E (0.51) ALDH1A1MEN1KMT2AHSD17B10TSHR
SCHEMBL2147241 0.80 KMT2A (0.50) ALDH1A1MEN1KMT2AHSD17B10TSHR
SCHEMBL161443 0.80 KMT2A (0.50) ALDH1A1MEN1KMT2AHSD17B10TSHR
SCHEMBL2794458 0.79 TSHR (0.50) ALDH1A1HSD17B10TSHRKDM4EHPGD
SCHEMBL10389063 0.79 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AHSD17B10TSHR
SCHEMBL23824155 0.79 KMT2A (0.49) ALDH1A1MEN1KMT2ATSHRKDM4E
SCHEMBL3356162 0.79 KMT2A (0.49) ALDH1A1MEN1KMT2AHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1044 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120324-A Preparation method of purified allopurinol 宜兴市星宇药业有限公司 2023-05-16 CN claimed
CN-114907315-A Synthesis method of Selitrectinib intermediate 重庆医科大学 2022-08-16 CN claimed
US-6846525-B2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 2005-01-25 US claimed
US-20040202825-A1 RECORDING SHEETS CONTAINING PURINE, PYRIMIDINE, BENZIMIDAZOLE, IMIDAZOLIDINE, URAZOLE, PYRAZOLE, TRIAZOLE, BENZOTRIAZOLE, TETRAZOLE, AND PYRAZINE COMPOUNDS XEROX CORPORATION 2004-10-14 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
CN-122094678-A AP 2-related kinase 1 inhibitors and uses thereof 2026-05-26 CN disclosed
WO-2026107328-A1 AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2026-05-21 WO disclosed
US-20260014125-A1 BICYCLIC-TYPE MAT2A INHIBITOR AND USE THEREOF HAIHE BIOPHARMA CO LTD (CN) 2026-01-15 US disclosed
EP-0001264-A1 Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation MERCK & CO. INC. (US) 1979-04-04 EP disclosed
US-4093617-A ENZYME INHIBITORS ICN PHARMACEUTICALS, INC. (US) 1978-06-06 US disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014125-A1 BICYCLIC-TYPE MAT2A INHIBITOR AND USE THEREOF MAT2A, MNAT1, MAT1A ALDH1A1 907/4885MEN1 589/4885KMT2A 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.