Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 5/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29259974 | 0.90 | CTSL (0.51) | HSD11B1CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL30981426 | 0.87 | HSD11B1 (0.52) | HSD11B1CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL30750698 | 0.87 | L3MBTL1 (0.52) | HSD11B1CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL7870 | 0.86 | L3MBTL1 (0.58) | HSD11B1CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL30732268 | 0.84 | SMN1; SMN2 (0.48) | NPSR1KMT2AMEN1JAK2JAK1 | |
| SCHEMBL951887 | 0.84 | HSD11B1 (0.65) | HSD11B1CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL3726979 | 0.84 | HSD11B1 (0.65) | HSD11B1CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL6944572 | 0.84 | HSD11B1 (0.65) | HSD11B1CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL29232309 | 0.84 | ALDH1A1 (0.53) | HSD11B1CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL29179827 | 0.83 | ALDH1A1 (0.49) | HSD11B1CTSLCTSBCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652161-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | Uppthera, Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155112-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | UPPTHERA, INC. (KR) | 2024-07-25 | — | — | WO | disclosed |