Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16397208 | 0.85 | SMN1; SMN2 (0.35) | L3MBTL1ALDH1A1RAB9APOLBKMT2A | |
| SCHEMBL16410303 | 0.80 | ATR (0.47) | L3MBTL1RAB9APOLBKMT2AKDM4E | |
| SCHEMBL30982180 | 0.78 | MAPT (0.46) | L3MBTL1ALDH1A1MAPTRAB9APOLB | |
| SCHEMBL30982115 | 0.78 | GPR35 (0.43) | NPSR1L3MBTL1ALDH1A1MAPTRAB9A | |
| SCHEMBL19127316 | 0.78 | MTNR1A (0.57) | NPSR1ELANEMTNR1AMTNR1B | |
| SCHEMBL14590706 | 0.76 | NPSR1 (0.52) | NPSR1L3MBTL1ELANEMAPTRAB9A | |
| SCHEMBL29215929 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9APOLBALOX15 | |
| SCHEMBL9250032 | 0.73 | RECQL (0.53) | NPSR1L3MBTL1ALDH1A1MAPTRAB9A | |
| SCHEMBL30791573 | 0.73 | RECQL (0.53) | NPSR1L3MBTL1ALDH1A1MAPTRAB9A | |
| SCHEMBL17117536 | 0.71 | NPSR1 (0.77) | NPSR1ALDH1A1MAPTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153595-A1 | CHROMANE DERIVATIVES AS EGFR SELECTIVE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-25 | — | — | WO | disclosed |