Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11873270 | 0.85 | CPA1 (0.38) | ALDH1A1CPA1TSHRTDP1LMNA | |
| SCHEMBL3789231 | 0.77 | CPA1 (0.52) | ALDH1A1CPA1TSHRTDP1 | |
| SCHEMBL8905407 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CPA1TSHRCYP3A4LMNA | |
| SCHEMBL2460939 | 0.76 | — | — | |
| SCHEMBL18095943 | 0.75 | — | — | |
| SCHEMBL17151671 | 0.75 | — | — | |
| SCHEMBL11045266 | 0.74 | ALDH1A1 (0.41) | ALDH1A1CPA1TSHRTDP1LMNA | |
| SCHEMBL17318330 | 0.73 | — | — | |
| SCHEMBL15178185 | 0.71 | LMNA (0.46) | METAP1TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL31509452 | 0.71 | LMNA (0.46) | METAP1TSHRCYP3A4NFKB1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367846-B2 | Method of producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367846-B2 | Method of producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367846-B2 | Method of producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-10-21 | — | — | US | disclosed |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-10-21 | — | — | US | disclosed |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-10-21 | — | — | US | disclosed |
| US-20100256098-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2010-10-07 | — | — | US | disclosed |
| US-20100256098-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2010-10-07 | — | — | US | disclosed |
| EP-2188296-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009029844-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009029844-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256098-A1 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS | WAPL, WDR1, DUSP1 | ALDH1A1 1064/4885CPA1 1626/4885METAP1 402/4885 |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | CBR3, CYP2E1, SULT2A1 | ALDH1A1 201/4885CPA1 3923/4885METAP1 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.