Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21198730 | 0.84 | ALDH1A1 (0.51) | FAAHGAAALDH1A1HTTKDM4E | |
| SCHEMBL12987195 | 0.83 | FAAH (0.51) | FAAHGAAALDH1A1HTTKDM4E | |
| SCHEMBL10604536 | 0.80 | CTSL (0.49) | FAAHGAAALDH1A1HTTKDM4E | |
| SCHEMBL29120775 | 0.80 | LMNA (0.53) | FAAHGAAALDH1A1HTTKDM4E | |
| SCHEMBL10590807 | 0.79 | CTSK (0.54) | FAAHGAAALDH1A1HTTKDM4E | |
| SCHEMBL867351 | 0.79 | FAAH (0.47) | FAAHGAAALDH1A1HTTKDM4E | |
| SCHEMBL30967279 | 0.78 | NAMPT (0.62) | GAAALDH1A1L3MBTL1MAPK1POLB | |
| SCHEMBL14744166 | 0.76 | FAAH (0.45) | FAAHGAAALDH1A1HTTKDM4E | |
| SCHEMBL24204344 | 0.76 | GAA (0.45) | FAAHGABRA5GAAALDH1A1HTT | |
| SCHEMBL16565618 | 0.75 | ATM (0.49) | FAAHGAAALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |