Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPRS1 | P07814 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | HAAO | P46952 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495727 | 1.00 | EPRS1 (0.41) | EPRS1CYP1A2ADRA2ACLCN2ALB | |
| SCHEMBL852651 | 0.84 | EPRS1 (0.44) | EPRS1CYP1A2ADRA2ACLCN2ALB | |
| SCHEMBL31094955 | 0.81 | CYP1A2 (0.44) | CYP1A2ALBCES2CES1TSHR | |
| SCHEMBL14472134 | 0.81 | CYP1A2 (0.44) | EPRS1CYP1A2ADRA2ACLCN2ALB | |
| SCHEMBL9277089 | 0.79 | NPC1 (0.42) | CES2CES1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL286718 | 0.79 | HAAO (0.42) | CYP1A2RXFP1TSHRNOTUMHAAO | |
| SCHEMBL29975434 | 0.79 | CES2 (0.45) | CYP1A2ALBCES2CES1TSHR | |
| SCHEMBL107175 | 0.79 | CES2 (0.50) | EPRS1CYP1A2ADRA2ACLCN2ALB | |
| SCHEMBL29465861 | 0.79 | CES2 (0.50) | EPRS1CYP1A2ADRA2ACLCN2ALB | |
| SCHEMBL3980826 | 0.79 | CYP1A2 (0.42) | EPRS1CYP1A2RXFP1TSHRHAAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |