Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336331 | 1.00 | RXRA (0.45) | RXRARXRGKIF11XDHTAS2R14 | |
| SCHEMBL29320291 | 0.85 | RXRA (0.55) | RXRARXRGKIF11XDHTAS2R14 | |
| SCHEMBL25983036 | 0.84 | KIF11 (0.52) | RXRARXRGKIF11XDHTAS2R14 | |
| SCHEMBL1334073 | 0.84 | KIF11 (0.52) | RXRARXRGKIF11XDHTAS2R14 | |
| Cyanate SCHEMBL30681205 | 0.80 | CES2 (0.43) | KIF11TMPRSS4CES2PTGS1AR | |
| Water SCHEMBL21493255 | 0.79 | GABRA1 (0.50) | RXRARXRGKIF11CES2PTGS1 | |
| SCHEMBL3508773 | 0.79 | GABRA1 (0.60) | KIF11TTRALBMEN1KMT2A | |
| SCHEMBL29837993 | 0.77 | KIF11 (0.45) | RXRARXRGKIF11XDHTAS2R14 | |
| SCHEMBL628008 | 0.77 | KIF11 (0.45) | RXRARXRGKIF11XDHTAS2R14 | |
| SCHEMBL186842 | 0.77 | GABRA1 (0.52) | RXRARXRGKIF11CES2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024157953-A1 | SUBSTITUTED BENZENE COMPOUND | 第一三共株式会社 | 2024-08-02 | — | — | WO | disclosed |