Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995164 | 0.96 | PIK3CA (0.41) | NOD2NOD1MEN1KMT2AF10 | |
| SCHEMBL30995252 | 0.83 | PLA2G10 (0.42) | KDM4ESMN1; SMN2PLA2G10PLA2G2APIK3CA | |
| SCHEMBL12490981 | 0.82 | NOD2 (0.55) | NOD2NOD1MEN1KMT2AF10 | |
| SCHEMBL30995187 | 0.79 | NOD2 (0.49) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL30995156 | 0.79 | PLA2G10 (0.43) | MEN1KMT2AKDM4ESMN1; SMN2PLA2G10 | |
| SCHEMBL30995134 | 0.78 | CYP11B2 (0.46) | NOD2NOD1MEN1KMT2AF10 | |
| SCHEMBL30995157 | 0.77 | NOD2 (0.53) | NOD2NOD1MEN1KMT2AF10 | |
| SCHEMBL30995116 | 0.77 | NOD2 (0.42) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL30995214 | 0.76 | USP2 (0.43) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL15642774 | 0.74 | NOD2 (0.50) | NOD2NOD1MEN1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |