Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995112 | 0.97 | KDM5A (0.35) | KDM5ACYP11B2MCL1PGRL3MBTL1 | |
| SCHEMBL30995171 | 0.94 | CYP11B2 (0.38) | KDM5ACYP11B2MCL1NOTUMCCR2 | |
| SCHEMBL30995137 | 0.83 | WDR5 (0.36) | MCL1L3MBTL1HCAR3CCR2 | |
| SCHEMBL30995240 | 0.81 | ALDH1A1 (0.38) | L3MBTL1MAPK1HTTKDM4EALDH1A1 | |
| SCHEMBL30995203 | 0.80 | PKM (0.37) | MAPK1HTTKDM4EALDH1A1HPGD | |
| SCHEMBL30995195 | 0.80 | NOTUM (0.42) | CYP11B2MCL1L3MBTL1NOTUMALDH1A1 | |
| SCHEMBL30995218 | 0.79 | ALDH1A1 (0.40) | L3MBTL1MAPK1HTTKDM4EALDH1A1 | |
| SCHEMBL30995216 | 0.78 | ADORA3 (0.32) | PGR | |
| SCHEMBL30995197 | 0.77 | CYP11B2 (0.36) | CYP11B2MCL1PGRL3MBTL1HCAR3 | |
| SCHEMBL30995185 | 0.76 | MCL1 (0.46) | MCL1L3MBTL1HCAR3CCR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |