Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995156 | 0.95 | PLA2G10 (0.43) | PLA2G10PLA2G2AABL1PIK3CAPRKDC | |
| SCHEMBL30995228 | 0.83 | NOD2 (0.41) | PLA2G10PLA2G2APIK3CAPRKDCALDH1A1 | |
| SCHEMBL30995229 | 0.80 | ABL1 (0.37) | PLA2G10PLA2G2AABL1PIK3CAPRKDC | |
| SCHEMBL30995164 | 0.79 | PIK3CA (0.41) | PLA2G10PLA2G2APIK3CAPRKDCALDH1A1 | |
| SCHEMBL30194405 | 0.77 | DAO (0.57) | PLA2G10DAOMCL1ALDH1A1TSHR | |
| SCHEMBL30995119 | 0.75 | PIK3CA (0.38) | PLA2G10PLA2G2AABL1PIK3CAPRKDC | |
| SCHEMBL30995135 | 0.74 | ALDH1A1 (0.46) | PLA2G10DAOMCL1ALDH1A1TSHR | |
| SCHEMBL30995226 | 0.73 | CYP11B2 (0.53) | PLA2G10PLA2G2ADAOALDH1A1TSHR | |
| SCHEMBL30995232 | 0.72 | ALDH1A1 (0.55) | PLA2G10DAOMCL1ALDH1A1TSHR | |
| SCHEMBL30995185 | 0.71 | MCL1 (0.46) | DAOMCL1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |