SCHEMBL30995286

SCHEMBL30995286

COc1cc(C(=O)O)nc(N2CCN(C(=O)OC(C)(C)C)CC2)n1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.46
ACHE P22303 1/20 0.45
LMNA P02545 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
RBP4 P02753 2/20 0.45
TLR9 Q9NR96 2/20 0.44
TLR7 Q9NYK1 1/20 0.44
CKS1B P61024 2/20 0.44
SKP1 P63208 2/20 0.44
SKP2 Q13309 2/20 0.44
PTPN11 Q06124 1/20 0.44
GPR119 Q8TDV5 4/20 0.44
KIT P10721 1/20 0.42
PIK3CA P42336 2/20 0.42
MAPT P10636 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
KMT5A Q9NQR1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18153356 0.85 SUV39H2 (0.46) SLC2A1ACHETLR9TLR7CKS1B
SCHEMBL27700149 0.85 RBP4 (0.57) ACHERBP4CKS1BSKP1SKP2
SCHEMBL25864607 0.81 RBP4 (0.53) ACHERBP4CKS1BSKP1SKP2
SCHEMBL18036153 0.81 LMNA (0.55) LMNATDP1RBP4MAPT
SCHEMBL10297496 0.79 GPR119 (0.55) ACHELMNACKS1BSKP1SKP2
SCHEMBL7136906 0.78 ACHE (0.63) ACHECKS1BSKP1SKP2PTPN11
SCHEMBL3113677 0.77 LMNA (0.51) LMNATDP1RBP4PIK3CA
SCHEMBL27260592 0.77 CKS1B (0.47) SLC2A1ACHELMNACKS1BSKP1
SCHEMBL30720173 0.77 CKS1B (0.47) SLC2A1ACHELMNACKS1BSKP1
SCHEMBL18087219 0.77 ALDH1A1 (0.57) ACHELMNACKS1BSKP1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634169-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF Pfizer Inc. (US) 2025-10-22 EP disclosed
WO-2024127297-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF PFIZER INC. (US) 2024-06-20 WO disclosed