Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995442 | 0.84 | CRHR1 (0.35) | CRHR1MAT2AHRH3CYP1A2CYP2D6 | |
| SCHEMBL17678027 | 0.81 | CRHR1 (0.38) | CRHR1KMT2ACYP1A2PIK3CDPIK3CA | |
| SCHEMBL3389492 | 0.81 | ALDH1A1 (0.50) | CRHR1HRH3KMT2APIK3CDPIK3CA | |
| SCHEMBL19279762 | 0.81 | HTR7 (0.38) | CRHR1KMT2ACYP1A2GRM2PIK3CD | |
| SCHEMBL30995497 | 0.79 | LMNA (0.38) | HRH3CYP1A2CYP2D6HTR2AHTR2C | |
| SCHEMBL21025762 | 0.78 | CRHR1 (0.42) | CRHR1HRH3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL28217862 | 0.77 | CRHR1 (0.50) | CRHR1GRM2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30995456 | 0.77 | NOTUM (0.41) | MAT2APOLBKMT2ACYP1A2NR4A2 | |
| SCHEMBL30995500 | 0.75 | MAP4K4 (0.43) | CRHR1KMT2ACYP1A2 | |
| SCHEMBL5137202 | 0.75 | NPC1 (0.39) | CRHR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530224-A | Pyrimidinone compound and application thereof | 深圳安泰维生物医药有限公司 | 2024-08-23 | — | — | CN | disclosed |