Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.40 |
| ▸ | REN | P00797 | 3/20 | 0.40 |
| ▸ | NRP1 | O14786 | 1/20 | 0.39 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.37 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471842 | 0.91 | ACE (0.41) | ACERENNMUR2NMUR1PLK1 | |
| SCHEMBL29800433 | 0.90 | NRP1 (0.48) | NRP1NMUR2NMUR1F2PLK1 | |
| SCHEMBL30552516 | 0.90 | ACE (0.49) | ACENRP1 | |
| SCHEMBL30272488 | 0.89 | ACE (0.40) | ACERENNRP1NMUR2NMUR1 | |
| SCHEMBL31461877 | 0.89 | NTSR1 (0.43) | KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL30997453 | 0.89 | NTSR1 (0.45) | PLK1 | |
| SCHEMBL34466206 | 0.89 | BDKRB2 (0.44) | ACENRP1MC4RPLK1 | |
| SCHEMBL29450071 | 0.88 | ACE (0.40) | ACERENNRP1KDM4EF2 | |
| SCHEMBL30422984 | 0.88 | ACE (0.47) | ACENRP1 | |
| SCHEMBL30844020 | 0.88 | TSHR (0.39) | ACERENNRP1KDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240230663-A1 | METHODS, COMPOSITIONS, AND SYSTEMS FOR PROFILING OR PREDICTING AN IMMUNE RESPONSE | AVAIL BIO INC (US) | 2024-07-11 | — | — | US | disclosed |