Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24934089 | 0.85 | SMN1; SMN2 (0.53) | FGFR1ABHD16APDE4DRAB9ANPC1 | |
| SCHEMBL29218170 | 0.81 | FGFR1 (0.53) | FGFR1ABHD16APDE4DRAB9ANPC1 | |
| SCHEMBL14693601 | 0.72 | RAB9A (0.45) | FGFR1ABHD16ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14693420 | 0.72 | MAPT (0.46) | FGFR1ABHD16APDE4DRAB9ANPC1 | |
| SCHEMBL24933448 | 0.70 | SMN1; SMN2 (0.59) | FGFR1ABHD16APDE4DRAB9ANPC1 | |
| SCHEMBL29366393 | 0.69 | ALDH1A1 (0.51) | FGFR1ABHD16AMAPTHPGDGFER | |
| SCHEMBL29151107 | 0.69 | MAPT (0.53) | ABHD16ARAB9ANPC1SMN1; SMN2HPN | |
| SCHEMBL30745168 | 0.69 | MAPT (0.53) | ABHD16ARAB9ANPC1SMN1; SMN2HPN | |
| SCHEMBL14693559 | 0.68 | MAPK14 (0.44) | FGFR1PDE4DRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL25278504 | 0.67 | TOP1 (0.38) | RAB9AKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055926-A | ROCK2 inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2024-05-17 | — | — | CN | disclosed |