Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762572 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4256455 | 0.75 | GAA (0.72) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6510914 | 0.75 | KDM4E (0.65) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8566733 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7656248 | 0.72 | KDM4E (0.53) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9412479 | 0.72 | ALDH1A1 (0.72) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL18732826 | 0.72 | HTT (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9412738 | 0.72 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7969932 | 0.71 | MTNR1A (0.76) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3797821 | 0.71 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658262-A1 | BICYCLIC IMIDE COMPOUNDS AS TRPA1 INHIBITORS | D.E. Shaw Research, LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163333-A1 | BICYCLIC IMIDE COMPOUNDS AS TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC (US) | 2024-08-08 | — | — | WO | disclosed |