Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15746871 | 0.95 | TSHR (0.47) | ALDH1A1TSHRMAPK1CALM1TACR1 | |
| SCHEMBL14832470 | 0.86 | CYP19A1 (0.46) | ALDH1A1TSHRMAPK1CALM1TACR1 | |
| SCHEMBL12675936 | 0.81 | ENPP2 (0.44) | ALDH1A1TSHRMAPK1CALM1TACR1 | |
| SCHEMBL23507263 | 0.80 | TSHR (0.56) | ALDH1A1TSHRMAPK1CALM1TACR1 | |
| SCHEMBL29547354 | 0.79 | CALM1 (0.64) | ALDH1A1TSHRCALM1HTR7CAMKK2 | |
| SCHEMBL850832 | 0.79 | CALM1 (0.64) | ALDH1A1TSHRCALM1HTR7CAMKK2 | |
| SCHEMBL18705942 | 0.77 | HTR7 (0.37) | ALDH1A1TSHRMAPK1CALM1LMNA | |
| SCHEMBL23507393 | 0.77 | GRIN2D (0.51) | ALDH1A1TSHRMAPK1CALM1TACR1 | |
| SCHEMBL385286 | 0.76 | HRH3 (0.58) | ALDH1A1TSHRLMNAMAPTHRH3 | |
| SCHEMBL2528801 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001973-B2 | Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups | DEGUSSA AG (DE) | 2006-02-21 | — | — | US | claimed |
| US-20030187178-A1 | Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups | DEGUSSA AG (DE) | 2003-10-02 | — | — | US | claimed |
| US-6613863-B2 | Benzyltrialkylammonium carboxylate isocyanate trimerization catalysts | DEGUSSA AG (DE) | 2003-09-02 | — | — | US | claimed |
| US-20020120089-A1 | Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups | DEGUSSA AG (DE) | 2002-08-29 | — | — | US | claimed |
| EP-2693444-A1 | CONDUCTIVE COMPOSITION, CONDUCTIVE FILM USING CONDUCIVE COMPOSITION, AND METHOD FOR MANUFACTURING CONDUCTIVE FILM | FUJIFILM Corporation (JP) | 2014-02-05 | — | — | EP | disclosed |
| US-20140005396-A1 | N-HETEROCYCLIC CARBENE METALLACYCLE CATALYSTS AND METHODS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-01-02 | — | — | US | disclosed |
| US-8492552-B2 | N-heterocyclic carbene metallacycle catalysts and methods | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-07-23 | — | — | US | disclosed |
| US-20100197920-A1 | N-HETEROCYCLIC CARBENE METALLACYCLE CATALYSTS AND METHODS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-08-05 | — | — | US | disclosed |
| US-7001973-B2 | Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups | DEGUSSA AG (DE) | 2006-02-21 | — | — | US | disclosed |
| EP-1229016-B1 | Catalyst and process for the preparation of isocyanate groups containing polyisocyanates with low viscosity and reduced colour | DEGUSSA (DE) | 2006-01-11 | — | — | EP | disclosed |
| EP-1085030-B1 | Catalyst and process for preparing polyisocyanates having isocyanurate groups and low colouring | DEGUSSA (DE) | 2005-05-18 | — | — | EP | disclosed |
| US-6800714-B2 | TRIMERIZING A DIISOCYANATE IN THE PRESENCE OF QUATERNARY AMMONIUM HYDROXIDES OR ESTERS | DEGUSSA AG (DE) | 2004-10-05 | — | — | US | disclosed |
| US-20030187178-A1 | Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups | DEGUSSA AG (DE) | 2003-10-02 | — | — | US | disclosed |
| US-6613863-B2 | Benzyltrialkylammonium carboxylate isocyanate trimerization catalysts | DEGUSSA AG (DE) | 2003-09-02 | — | — | US | disclosed |
| US-20030158368-A1 | Catalyst and process for preparing color-reduced polyisocyanates containing isocyanurate groups | DEGUSA AG (DE) | 2003-08-21 | — | — | US | disclosed |
| US-20030153714-A1 | Catalyst and process for preparing color-reduced polyisocyanates containing isocyanurate groups | DEGUSA AG (DE) | 2003-08-14 | — | — | US | disclosed |
| US-6552154-B1 | Trimerizing at least one diisocyanate in presence of such as N-(2-hydroxypropyl)-N,N-dimethyl-N-(3-methoxybenzyl)ammonium 2-ethylhexanoate | DEGUSSA AG (DE) | 2003-04-22 | — | — | US | disclosed |
| US-20020120089-A1 | Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups | DEGUSSA AG (DE) | 2002-08-29 | — | — | US | disclosed |
| EP-1229016-A2 | Catalyst and process for the preparation of isocyanate groups containing polyisocyanates with low viscosity and reduced colour | Degussa AG (DE) | 2002-08-07 | — | — | EP | disclosed |
| EP-1085030-A2 | Catalyst and process for preparing polyisocyanates having isocyanurate groups and low colouring | Degussa-Hüls Aktiengesellschaft (DE) | 2001-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005396-A1 | N-HETEROCYCLIC CARBENE METALLACYCLE CATALYSTS AND METHODS | NIM1K, GNE, NBAS | ALDH1A1 2892/4885TSHR 4668/4885MAPK1 4634/4885 |
| US-20100197920-A1 | N-HETEROCYCLIC CARBENE METALLACYCLE CATALYSTS AND METHODS | NIM1K, GNE, NBAS | ALDH1A1 2892/4885TSHR 4665/4885MAPK1 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.