Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100559 | 0.86 | KEAP1 (0.51) | METAP1METAP2ALDH1A1KDM4EKMT2A | |
| SCHEMBL2880728 | 0.81 | KDM4E (0.43) | METAP1METAP2KDM4EPTGS2L3MBTL1 | |
| SCHEMBL27541104 | 0.80 | METAP2 (0.56) | METAP1METAP2ALDH1A1KDM4EKMT2A | |
| SCHEMBL6512183 | 0.79 | KDM4E (0.44) | METAP1ALDH1A1KDM4EKMT2ATDP1 | |
| SCHEMBL28752448 | 0.79 | KDM4E (0.42) | METAP1METAP2KDM4EPTGS2L3MBTL1 | |
| SCHEMBL1360826 | 0.76 | LMNA (0.41) | METAP1ALDH1A1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL6220452 | 0.76 | TDP1 (0.43) | METAP1ALDH1A1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL3857735 | 0.76 | LMNA (0.41) | METAP1ALDH1A1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL1407984 | 0.76 | KDM4E (0.41) | METAP1ALDH1A1KDM4EKMT2ATDP1 | |
| SCHEMBL538501 | 0.76 | PDE4A (0.44) | METAP1METAP2KDM4EKMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204535-B1 | N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-08-19 | — | — | EP | claimed |
| WO-2022232195-A2 | COVALENT APTAMERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-11-03 | — | — | WO | disclosed |
| US-RE35177-E | N-fluoropyridinium salt and process for preparing same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0494770-B1 | Method for preparing N-fluoropyridinium salts | ONODA CEMENT CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5336772-A | Reacting pyridine compound, fluorine and Bronsted acid in specified ratios | ONODA CEMENT CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0204535-B1 | N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-08-19 | — | — | EP | disclosed |
| EP-0494770-A1 | Method for preparing N-fluoropyridinium salts | ONODA CEMENT COMPANY, LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-4996320-A | Thyroid inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-02-26 | — | — | US | disclosed |
| CN-1042144-A | Pesticidal compound | ICI PLC (GB) | 1990-05-16 | — | — | CN | disclosed |
| EP-0204535-A1 | N-fluoropyridinium salt and process for preparing same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-10 | — | — | EP | disclosed |