Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proline SCHEMBL4604674 | 0.86 | TLR2 (0.34) | TLR2 | |
| SCHEMBL2043828 | 0.86 | NOS2 (0.37) | TLR2 | |
| Proline SCHEMBL140698 | 0.85 | TLR2 (0.34) | TLR2 | |
| Alanine SCHEMBL5970554 | 0.81 | TLR2 (0.36) | TLR2 | |
| Proline SCHEMBL12813264 | 0.81 | TLR2 (0.31) | TLR2 | |
| Proline SCHEMBL3519298 | 0.81 | TLR2 (0.32) | TLR2 | |
| Asparagine SCHEMBL4995021 | 0.80 | NOS2 (0.32) | TLR2 | |
| Serine SCHEMBL181142 | 0.79 | NOS2 (0.32) | — | |
| SCHEMBL6520768 | 0.79 | TLR2 (0.31) | TLR2 | |
| Glutamic Acid SCHEMBL16934712 | 0.79 | GRM8 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006170-B2 | Compositions for elastogenesis and connective tissue treatment | HUMAN MATRIX SCIENCES, LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-7803522-B2 | Elastin producing fibroblast formulations and methods of using the same | HUMAN MATRIX SCIENCES, LLC (US) | 2010-09-28 | — | — | US | disclosed |
| US-7560430-B2 | To stimulate the endogenous production of Elastin or appear to enhance the elasticity of the skin | HUMAN MATRIX SCIENCES, LLC (US) | 2009-07-14 | — | — | US | disclosed |
| US-20080050346-A1 | Elastin producing fibroblast formulations and methods of using the same | NULASTIN, INC. | 2008-02-28 | — | — | US | disclosed |