Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527857 | 0.85 | TLR2 (0.35) | TLR2 | |
| Proline SCHEMBL4604674 | 0.79 | TLR2 (0.34) | TLR2 | |
| SCHEMBL3100834 | 0.79 | TLR2 (0.30) | TLR2 | |
| Glutamic Acid SCHEMBL16934712 | 0.78 | GRM8 (0.35) | — | |
| Proline SCHEMBL12813264 | 0.78 | TLR2 (0.31) | TLR2 | |
| Alanine SCHEMBL5970554 | 0.77 | TLR2 (0.36) | TLR2 | |
| SCHEMBL1887227 | 0.76 | NOS2 (0.40) | TLR2 | |
| Proline SCHEMBL7043240 | 0.75 | NOS2 (0.33) | — | |
| SCHEMBL8815155 | 0.75 | TLR2 (0.31) | TLR2 | |
| Leucine SCHEMBL6463328 | 0.74 | SLC7A5 (0.44) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050164969-A1 | Method of extending life span | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-07-28 | — | — | US | disclosed |