Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043828 | 0.94 | NOS2 (0.37) | TLR2NOS2NOS3NOS1PRCP | |
| Proline SCHEMBL140698 | 0.90 | TLR2 (0.34) | TLR2NOS2NOS3NOS1PRCP | |
| Proline SCHEMBL3519298 | 0.85 | TLR2 (0.32) | TLR2NOS2NOS3NOS1ELANE | |
| SCHEMBL527857 | 0.83 | TLR2 (0.35) | TLR2PRCPMEN1KMT2ACYP1A2 | |
| Lysine SCHEMBL6151465 | 0.83 | GSR (0.49) | TLR2DPP7DPP4 | |
| Phenylalanine SCHEMBL5672080 | 0.81 | SLC7A5 (0.51) | DPP7SLC7A5ELANEDPP4SLC1A5 | |
| SCHEMBL3100834 | 0.81 | TLR2 (0.30) | TLR2 | |
| SCHEMBL10363588 | 0.81 | RAB9A (0.39) | TLR2NOS2NOS3NOS1PRCP | |
| SCHEMBL3714016 | 0.81 | RAB9A (0.39) | TLR2NOS2NOS3NOS1PRCP | |
| SCHEMBL23407548 | 0.80 | NOS2 (0.35) | TLR2NOS2NOS3NOS1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1151102-B1 | GLYCOSYLATED LEPTIN COMPOSITIONS AND RELATED METHODS | AMGEN INC (US) | 2006-04-19 | — | — | EP | disclosed |