Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.32 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435767 | 0.84 | KDM4E (0.39) | PDE4DPDE7ACHRM1NR1I2SMARCA2 | |
| SCHEMBL25278645 | 0.84 | KDM4C (0.35) | KDM4CEP300CREBBPNPC1RAB9A | |
| SCHEMBL21058017 | 0.84 | GABRA5 (0.40) | KDM4CPDE4DPDE7AEP300CREBBP | |
| SCHEMBL30740368 | 0.81 | TGFBR1 (0.44) | KDM4CALOX15NPC1RAB9AKDM4E | |
| SCHEMBL19715757 | 0.81 | SLCO1B1 (0.38) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29411759 | 0.81 | SLCO1B1 (0.38) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL22806839 | 0.80 | SLCO1B1 (0.41) | KDM4CCREBBPMEN1KMT2ANPC1 | |
| SCHEMBL21058053 | 0.78 | LPAR1 (0.40) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL25422781 | 0.78 | SLCO1B1 (0.39) | KDM4CPDE4DPDE7AMEN1KMT2A | |
| SCHEMBL25231360 | 0.78 | SLCO1B1 (0.35) | KDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112055711-B | Cyclohexylic acid triazolazine as LPA antagonist | 百时美施贵宝公司 | 2024-07-23 | — | — | CN | disclosed |