SCHEMBL31010604

SCHEMBL31010604

Cc1ccc2c(NCc3ncco3)nc(Cl)nn12

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 1/20 0.36
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
EGFR P00533 1/20 0.30
KDR P35968 1/20 0.30
DPP4 P27487 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31010595 0.88 TLR7 (0.37) TLR7SMN1; SMN2
SCHEMBL31010601 0.88 TLR7 (0.37) TLR7SMN1; SMN2
SCHEMBL30997374 0.78 PDE10A (0.43) KDR
SCHEMBL31010619 0.77 PDE10A (0.46) TLR7
SCHEMBL30997378 0.76 KCNH3 (0.38) CYP1A2CYP3A4CYP2C19EGFRKDR
SCHEMBL31010597 0.76 HRH4 (0.41) TLR7CYP2C19SMN1; SMN2
SCHEMBL30948919 0.76 APP (0.49)
SCHEMBL31010594 0.73 TLR7 (0.33) TLR7
SCHEMBL30948908 0.72 TP53 (0.44) CYP1A2CYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL30997392 0.72 KCNH3 (0.41) SMN1; SMN2EGFRKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651952-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2024155844-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed