Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997364 | 0.86 | KCNH3 (0.38) | KCNH3ADORA3CDK2JAK2IGF1R | |
| SCHEMBL30997374 | 0.83 | PDE10A (0.43) | ADORA2ACHRM4KDRPDE2ALMNA | |
| SCHEMBL31010619 | 0.77 | PDE10A (0.46) | — | |
| SCHEMBL30997392 | 0.77 | KCNH3 (0.41) | KCNH3EGFRKDRPDE2ANAMPT | |
| SCHEMBL31010604 | 0.76 | TLR7 (0.36) | EGFRKDRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31010597 | 0.76 | HRH4 (0.41) | ADORA2AADORA2BCHRM4ADORA3CYP2C19 | |
| SCHEMBL30948919 | 0.76 | APP (0.49) | PLK1LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL30948908 | 0.72 | TP53 (0.44) | ADORA3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30997398 | 0.72 | KCNH3 (0.32) | KCNH3PDE1APDE1BPDE1CRXRA | |
| SCHEMBL17933827 | 0.69 | CDK1 (0.40) | KCNH3PDE1APDE1BPDE1CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651950-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | Skyhawk Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155842-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |