SCHEMBL3102269

SCHEMBL3102269

CCCCC1(CC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2cccc(N)c2)C1O

nearest known ligand 0.93

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12196445 1.00 SLC10A2 (0.93) SLC10A2
SCHEMBL12196447 1.00 SLC10A2 (0.93) SLC10A2
SCHEMBL10013951 1.00 SLC10A2 (0.93) SLC10A2
SCHEMBL12196461 1.00 SLC10A2 (0.93) SLC10A2
SCHEMBL12196590 1.00 SLC10A2 (0.93) SLC10A2
SCHEMBL347340 0.96 SLC10A2 (1.00) SLC10A2
SCHEMBL10013953 0.96 SLC10A2 (1.00) SLC10A2
SCHEMBL9961496 0.90 SLC10A2 (1.00) SLC10A2
SCHEMBL3102256 0.89 SLC10A2 (0.77) SLC10A2
SCHEMBL19789688 0.88 SLC10A2 (0.79) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7803792-B2 Quaternary ammonium compounds ASAHI KASEI PHARMA CORPORATION (JP) 2010-09-28 US disclosed
US-7312208-B2 Quaternary ammonium compounds ASAHI KASEI PHARMA CORPORATION (JP) 2007-12-25 US disclosed
US-20070203115-A1 Novel quaternary ammonium compounds ASAHI KASEI PHARMA CORPORATION (JP) 2007-08-30 US disclosed
EP-1345932-B1 DIPHENYL AZETIDINONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THEIR USE SANOFI AVENTIS DEUTSCHLAND (DE) 2006-10-18 EP disclosed
CN-1678597-A Novel quaternary ammonium compounds ASAHI KASEI PHARMA CORP (JP) 2005-10-05 CN disclosed
EP-1535913-A1 NOVEL QUATERNARY AMMONIUM COMPOUNDS Asahi Kasei Pharma Corporation (JP) 2005-06-01 EP disclosed
EP-1345932-A1 DIPHENYL AZETIDINONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THEIR USE Aventis Pharma Deutschland GmbH (DE) 2003-09-24 EP disclosed
US-6498156-B2 TREATING HYPERLIPIDEMIA, ARTERIOSCLEROSIS AND HYPERCHOLESTEROLEMIA AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-12-24 US disclosed
US-20020128252-A1 Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2002-09-12 US disclosed
WO-2002050068-A1 DIPHENYL AZETIDINONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THEIR USE AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203115-A1 Novel quaternary ammonium compounds SLC10A2, SLC10A1, ABCB11 SLC10A2 1/4885
US-20020128252-A1 Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use QDPR, NDUFB6, NDUFB7 SLC10A2 2523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.