SCHEMBL3102322

SCHEMBL3102322

Fc1ccc(-c2cc(-n3c4ccccc4c4ccccc43)ccn2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 2/20 0.43
MCL1 Q07820 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
MAPK14 Q16539 4/20 0.39
CYP19A1 P11511 1/20 0.39
BCHE P06276 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
COMT P21964 1/20 0.36
GRM5 P41594 1/20 0.36
MAPKAPK2 P49137 1/20 0.36
TOP1 P11387 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19972423 0.88 L3MBTL1 (0.50) TGFBR1MCL1L3MBTL1KDM4EATM
SCHEMBL30376996 0.88 L3MBTL1 (0.50) TGFBR1MCL1L3MBTL1KDM4EATM
SCHEMBL15469063 0.84 KDM4E (0.52) MCL1L3MBTL1KDM4EATMCOMT
SCHEMBL19349630 0.82 KDM4E (0.47) MCL1L3MBTL1KDM4EATMCOMT
SCHEMBL3105471 0.82 MAPK14 (0.44) TGFBR1MCL1L3MBTL1KDM4EATM
SCHEMBL17952918 0.80 KDM4E (0.48) TGFBR1L3MBTL1KDM4EATMMAPT
SCHEMBL12036268 0.79 ASIC3 (0.42) TGFBR1MCL1L3MBTL1KDM4EATM
SCHEMBL16689510 0.79 MAPT (0.39) MCL1L3MBTL1KDM4EATMMAPK14
SCHEMBL17030452 0.79 GPR3 (0.43) L3MBTL1KDM4EATMMAPK14MAPT
SCHEMBL17952728 0.78 KDM4E (0.43) TGFBR1L3MBTL1KDM4EATMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8232549-B2 Iridium complex containing carbazole-substituted pyridine and phenyl derivatives as main ligand and organic light-emitting diodes containing the same INKTEC CO., LTD (KR) 2012-07-31 US disclosed
US-8232549-B2 Iridium complex containing carbazole-substituted pyridine and phenyl derivatives as main ligand and organic light-emitting diodes containing the same INKTEC CO., LTD (KR) 2012-07-31 US disclosed
US-8232549-B2 Iridium complex containing carbazole-substituted pyridine and phenyl derivatives as main ligand and organic light-emitting diodes containing the same INKTEC CO., LTD (KR) 2012-07-31 US disclosed
US-20100270540-A1 Iridium Complex Containing Carbazole-Substituted Pyridine and Phenyl Derivatives as Main Ligand and Organic Light-Emitting Diodes Containing the Same INKTEC CO., LTD. (KR) 2010-10-28 US disclosed
US-20100270540-A1 Iridium Complex Containing Carbazole-Substituted Pyridine and Phenyl Derivatives as Main Ligand and Organic Light-Emitting Diodes Containing the Same INKTEC CO., LTD. (KR) 2010-10-28 US disclosed
US-20100270540-A1 Iridium Complex Containing Carbazole-Substituted Pyridine and Phenyl Derivatives as Main Ligand and Organic Light-Emitting Diodes Containing the Same INKTEC CO., LTD. (KR) 2010-10-28 US disclosed
WO-2009072821-A2 IRIDIUM COMPLEX CONTAINING CARBAZOLE-SUBSTITUTED PYRIDINE AND PHENYL DERIVATIVES AS MAIN LIGAND AND ORGANIC LIGHT-EMITTING DIODES CONTAINING THE SAME INKTEC CO., LTD. (KR) 2009-06-11 WO disclosed
WO-2009072821-A2 IRIDIUM COMPLEX CONTAINING CARBAZOLE-SUBSTITUTED PYRIDINE AND PHENYL DERIVATIVES AS MAIN LIGAND AND ORGANIC LIGHT-EMITTING DIODES CONTAINING THE SAME INKTEC CO., LTD. (KR) 2009-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100270540-A1 Iridium Complex Containing Carbazole-Substituted Pyridine and Phenyl Derivatives as Main Ligand and Organic Light-Emitting Diodes Containing the Same PDCD5, MAP1LC3B, MAP1LC3A TGFBR1 734/4885MCL1 2206/4885L3MBTL1 423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.