Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023665 | 0.94 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDCYP2C9ALOX15 | |
| SCHEMBL31023851 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDCYP2C9ALOX15 | |
| SCHEMBL31023918 | 0.82 | OPRD1 (0.36) | ALDH1A1MGLLOPRM1OPRD1OPRK1 | |
| SCHEMBL31023706 | 0.78 | OPRD1 (0.33) | MGLLOPRM1OPRD1OPRK1CHRM2 | |
| SCHEMBL31023947 | 0.75 | OPRM1 (0.41) | ALDH1A1HPGDOPRM1OPRD1CHRM2 | |
| SCHEMBL31023708 | 0.71 | MGLL (0.48) | ALDH1A1KDM4EHPGDMGLLKMT2A | |
| SCHEMBL4693977 | 0.68 | TSHR (0.57) | ALDH1A1KDM4EHPGDCYP2C19KMT2A | |
| SCHEMBL31023711 | 0.67 | SCD5 (0.37) | HPGDMAPT | |
| SCHEMBL9047536 | 0.67 | ALDH1A1 (0.58) | ALDH1A1KDM4ECYP2C19KMT2AOPRM1 | |
| SCHEMBL16744474 | 0.66 | MGLL (0.51) | ALDH1A1HPGDMGLLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665718-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024168426-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2024-08-22 | — | — | WO | disclosed |