Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 6/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.46 |
| ▸ | JAK2 | O60674 | 3/20 | 0.46 |
| ▸ | JAK1 | P23458 | 3/20 | 0.45 |
| ▸ | JAK3 | P52333 | 3/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25417862 | 1.00 | DYRK1A (0.47) | DYRK1AFEN1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL17767937 | 0.77 | JAK2 (0.53) | DYRK1AJAK2CDK5CDK5R1 | |
| Hydrochloric Acid SCHEMBL22836886 | 0.76 | JAK2 (0.52) | DYRK1AJAK2CDK5CDK5R1 | |
| SCHEMBL30373746 | 0.75 | FEN1 (0.50) | FEN1PIK3CDPIK3CAPIK3CGIKBKE | |
| SCHEMBL25416405 | 0.75 | FEN1 (0.50) | FEN1PIK3CDPIK3CAPIK3CGIKBKE | |
| SCHEMBL14321130 | 0.75 | FEN1 (0.49) | FEN1PIK3CDPIK3CAPIK3CGIKBKE | |
| SCHEMBL15885689 | 0.73 | MET (0.45) | FEN1PIK3CDPIK3CAPIK3CGIKBKE | |
| SCHEMBL21425565 | 0.73 | CSF1R (0.53) | — | |
| SCHEMBL6596348 | 0.71 | DYRK1A (0.46) | DYRK1ACDK5CDK5R1 | |
| SCHEMBL14396769 | 0.71 | PIK3CA (0.52) | FEN1PIK3CDPIK3CAPIK3CGIKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129067-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| CN-118475580-A | Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof | 普罗根托斯治疗公司 | 2024-08-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129067-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | PDGFRB, PDGFRA, PDGFA | DYRK1A 1316/4885FEN1 4452/4885PIK3CD 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.