SCHEMBL3102409

SCHEMBL3102409

Nc1ccccc1-c1cccnn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
IDO1 P14902 4/20 0.44
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 3/20 0.42
GAA P10253 3/20 0.42
HSD17B10 Q99714 2/20 0.42
ATAD2 Q6PL18 1/20 0.40
HDAC4 P56524 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
RAB9A P51151 2/20 0.38
HTR2C P28335 2/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GOT1 P17174 1/20 0.38
HPGD P15428 1/20 0.37
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29943503 1.00 ALDH1A1 (0.54) ALDH1A1L3MBTL1IDO1KDM4ENPC1
SCHEMBL6017122 0.78 ALDH1A1 (0.52) ALDH1A1L3MBTL1IDO1KDM4ENPC1
SCHEMBL3322710 0.76 HDAC4 (0.38) ALDH1A1L3MBTL1KDM4EHSD17B10HDAC4
SCHEMBL3704382 0.75 HTR2C (0.38) GAAHDAC4HTR2CMEN1KMT2A
SCHEMBL34461976 0.75 GABRG2 (0.47) ALDH1A1L3MBTL1IDO1KDM4ENPC1
SCHEMBL8138036 0.75 IDO1 (0.44) ALDH1A1IDO1HSD17B10SMN1; SMN2RAB9A
SCHEMBL30717913 0.75 IDO1 (0.44) ALDH1A1IDO1HSD17B10SMN1; SMN2RAB9A
SCHEMBL8893831 0.75 LMNA (0.48) ALDH1A1IDO1KDM4ENPC1GAA
SCHEMBL3464878 0.75 NPC1 (0.45) ALDH1A1L3MBTL1IDO1KDM4ENPC1
SCHEMBL29942556 0.75 IDO1 (0.44) ALDH1A1IDO1HSD17B10SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115943190-A Multifunctional material for temporary bonding 布鲁尔科技公司 2023-04-07 CN claimed
WO-2024058617-A1 ANTIVIRAL USE OF HETEROARYL DERIVATIVE COMPOUND 일동제약(주) 2024-03-21 WO disclosed
WO-2024019541-A1 HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF 일동제약(주) 2024-01-25 WO disclosed
CN-110462401-B Use of enhancers of cellular autophagy for sensitizing tumors to radiotherapy 古斯塔夫·鲁西研究所 2023-01-17 CN disclosed
US-11517575-B2 Use of minaprine to reduce tumor growth INSTITUT GUSTAVE ROUSSY (FR) 2022-12-06 US disclosed
US-11471463-B2 Enhancers of cellular cannibalism for use to sensitize tumors to radiation therapy INSTITUT GUSTAVE ROUSSY (FR) 2022-10-18 US disclosed
CN-110249004-B Polyimide precursor composition 东京应化工业株式会社 2022-07-19 CN disclosed
CN-108389512-B Laminate, flexible device, and method for producing laminate 东京应化工业株式会社 2022-04-15 CN disclosed
CN-108387954-B Laminate, flexible device, and method for producing laminate 东京应化工业株式会社 2022-01-18 CN disclosed
EP-3743721-B1 MINAPRINE FOR USE IN REDUCING TUMOR GROWTH ROUSSY INST GUSTAVE (FR) 2021-11-17 EP disclosed
EP-1693434-A2 Soot dispersants and lubricating oil compositions containing same Infineum International Limited (GB) 2006-08-23 EP disclosed
US-20060116299-A1 Lubricating oil compositions INFINEUM INTERNATIONAL LIMITED (GB) 2006-06-01 US disclosed
US-20060116300-A1 Lubricating oil compositions INFINEUM INTERNATIONAL LIMITED (GB) 2006-06-01 US disclosed
EP-1661970-A1 Lubricating Oil Compositions Infineum International Limited (GB) 2006-05-31 EP disclosed
EP-1661969-A1 Lubricating oil compositions Infineum International Limited (GB) 2006-05-31 EP disclosed
EP-1621602-A1 Lubricating oil compositions Infineum International Limited (GB) 2006-02-01 EP disclosed
US-20050119138-A1 Lubricating oil compositions RITCHIE ANDREW J (US) 2005-06-02 US disclosed
EP-1398365-A2 Lubricating oil compositions for EGR equipped diesel engines Infineum International Limited (GB) 2004-03-17 EP disclosed
EP-0223974-A1 N-Substituted-N-[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)-phenyl]alkanamides, carbamates and ureas AMERICAN CYANAMID COMPANY (US) 1987-06-03 EP disclosed
US-3947437-A Substituted pyridazinyloxy(thio)phenyl ureas and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11517575-B2 Use of minaprine to reduce tumor growth METAP1, METAP2, CMA1 ALDH1A1 1147/4885L3MBTL1 1857/4885IDO1 201/4885
US-11471463-B2 Enhancers of cellular cannibalism for use to sensitize tumors to radiation therapy CMA1, LY96, CD74 ALDH1A1 2899/4885L3MBTL1 3071/4885IDO1 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.