Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GOT1 | P17174 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8425421 | 0.98 | HTR2C (0.37) | HTR2CHTR2ACYP11B2HTR2BCASP6 | |
| Hydrochloric Acid SCHEMBL10877717 | 0.96 | HTR2C (0.36) | HTR2CHTR2ACYP11B2HTR2BCASP6 | |
| SCHEMBL20472405 | 0.76 | CNR2 (0.47) | BLMP2RX7 | |
| SCHEMBL3102409 | 0.75 | ALDH1A1 (0.54) | HTR2CHTR2ACYP11B2MEN1KMT2A | |
| SCHEMBL29943503 | 0.75 | ALDH1A1 (0.54) | HTR2CHTR2ACYP11B2MEN1KMT2A | |
| SCHEMBL29442588 | 0.74 | GOT1 (0.46) | HTR2CHTR2ACYP11B2HTR2BCASP6 | |
| SCHEMBL30792004 | 0.74 | GOT1 (0.46) | HTR2CHTR2ACYP11B2HTR2BCASP6 | |
| SCHEMBL1456807 | 0.74 | GOT1 (0.46) | HTR2CHTR2ACYP11B2HTR2BCASP6 | |
| SCHEMBL2482338 | 0.72 | KDM4E (0.54) | BLMKMT2ATDP1 | |
| SCHEMBL28845072 | 0.72 | FAAH (0.41) | HTR2CHTR2AHTR2BCASP6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118355110-A | Method for producing cartilage and bone | 默多克儿童研究所 | 2024-07-16 | — | — | CN | claimed |
| WO-2023190663-A1 | HIGH-PURITY COMPOUND PRODUCTION METHOD AND PURIFICATION METHOD | 参天製薬株式会社 | 2023-10-05 | — | — | WO | claimed |
| CN-110678182-B | Pharmaceutical composition containing a compound capable of penetrating the blood-brain barrier as an active ingredient for preventing or treating brain cancer | 大邱庆北尖端医疗产业振兴财团 | 2022-08-23 | — | — | CN | claimed |
| CN-109219608-B | Fused pentacyclic imidazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-110678182-A | Pharmaceutical composition containing a compound capable of penetrating the blood-brain barrier as an active ingredient for preventing or treating brain cancer | 大邱庆北尖端医疗产业振兴财团 | 2020-01-10 | — | — | CN | claimed |
| EP-1100480-B1 | MUSCARINIC ANTAGONISTS IN THE TREATMENT OF PRESBYOPIA | ALLERGAN INC (US) | 2003-09-24 | — | — | EP | claimed |
| EP-0634932-B1 | METHOD FOR REDUCING INTRAOCULAR PRESSURE IN THE MAMMALIAN EYE BY ADMINISTRATION OF MUSCARINIC ANTAGONISTS | ALLERGAN INC (US) | 2002-06-19 | — | — | EP | claimed |
| EP-1148880-A2 | METHODS FOR RESTORING AND/OR ENHANCING ACCOMMODATION IN PSEUDO PHAKIA | Allergan Sales, Inc. (US) | 2001-10-31 | — | — | EP | claimed |
| EP-0672666-B1 | Imidazodiazepins | HOFFMANN LA ROCHE (CH) | 2001-07-25 | — | — | EP | claimed |
| WO-2000044379-A2 | METHODS FOR RESTORING AND/OR ENHANCING ACCOMMODATION IN PSEUDO PHAKIA | ALLERGAN SALES, INC. (US) | 2000-08-03 | — | — | WO | claimed |
| US-5885986-A | CLEAVING, N-ALKYLATING AND REDUCING THE INTERMEDIATE FORMED BY REACTING AN OXAZOLYL AND THIAZOLYLIMIDAZOBENZO AND THIENODIAZEPINE DERIVATIVES WITH AMINE COMPOUNDS; USED AS ANXIOLYTIC AND ANTICONVULSANT OR SEDATIVE-HYPNOTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-03-23 | — | — | US | claimed |
| US-5716952-A | TOPICAL APPLICATION | ALLERGAN (US) | 1998-02-10 | — | — | US | claimed |
| EP-0548125-A1 | SUBSTITUTED 6,7-DIHYDROIMIDAZO(1,5,4-EF)(1,5)BENZODIAZEPIN-6-ONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | Pfizer Limited (GB) | 1993-06-30 | — | — | EP | claimed |
| US-4424226-A | ANTIULCER AGENTS | DR. KARL THOMAE GMBH (DE) | 1984-01-03 | — | — | US | claimed |
| JP-53095997-A | — | — | None | — | — | JP | disclosed |
| JP-53095996-A | — | — | None | — | — | JP | disclosed |
| CN-118355110-A | Method for producing cartilage and bone | 默多克儿童研究所 | 2024-07-16 | — | — | CN | disclosed |
| US-4154833-A | INDOMETHACIN (1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOLE-3-ACETIC ACID) WITH PIRENZEPINE (5,11-DIHYDRO-11-((4-METHYL-1-PIPERAZINYL)-ACETYL)-6H-PYRIDO(2,3 -B)(1,4)BENZODIAZEPIN-6-ONE) | BOEHRINGER INGELHEIM GMBH (DE) | 1979-05-15 | — | — | US | disclosed |
| JP-S5395996-A | PREPARATION OF NOVEL IMIDAZOBENZODIAZEPIN DERIVATIVES | TEIJIN LTD | 1978-08-22 | — | — | JP | disclosed |
| JP-S5395997-A | NOVEL IMIDAZOBENZODIAZEPIN DERIVATIVES | TEIJIN LTD | 1978-08-22 | — | — | JP | disclosed |