SCHEMBL31024719

SCHEMBL31024719

COC(=O)c1cc2c(cc1C)OC1(CCN(C(=O)OC(C)(C)C)CC1)CO2

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.42
▸ GPR119 Q8TDV5 9/20 0.41
▸ IDO1 P14902 2/20 0.41
▸ EED O75530 1/20 0.39
▸ RBBP4 Q09028 1/20 0.39
▸ SUZ12 Q15022 1/20 0.39
▸ EZH2 Q15910 1/20 0.39
▸ AEBP2 Q6ZN18 1/20 0.39
▸ HRH3 Q9Y5N1 1/20 0.38
▸ GPR183 P32249 1/20 0.37
▸ LMNA P02545 1/20 0.36
▸ MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31024681 1.00 PKM (0.42) PKMGPR119IDO1EEDRBBP4
SCHEMBL31024717 0.94 GPR119 (0.43) PKMGPR119IDO1EEDRBBP4
SCHEMBL25345030 0.90 EED (0.36) PKMGPR119IDO1EEDRBBP4
SCHEMBL31024662 0.90 EED (0.36) PKMGPR119IDO1EEDRBBP4
SCHEMBL31024668 0.90 EED (0.36) PKMGPR119IDO1EEDRBBP4
SCHEMBL31024669 0.88 GPR119 (0.40) PKMGPR119IDO1EEDRBBP4
SCHEMBL31738784 0.86 GPR119 (0.42) PKMGPR119IDO1HRH3GPR183
SCHEMBL25343334 0.83 KMT2A (0.49) PKMGPR119
SCHEMBL25342621 0.83 KMT2A (0.49) PKMGPR119
SCHEMBL30591605 0.82 PKM (0.43) PKMGPR119EEDRBBP4SUZ12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4656642-A1 ESTROGEN RECEPTOR PROTEOLYSIS TARGETING CHIMERA COMPOUND AND USE THEREOF GAN & LEE PHARM CO., LTD (CN) 2025-12-03 — — EP disclosed
WO-2025026283-A1 COMPOUND FOR SELECTIVELY DEGRADING SMARCA2/4 AND USE THEREOF 甘李药业股份有限公司 2025-02-06 — — WO disclosed
WO-2024156294-A1 ESTROGEN RECEPTOR PROTEOLYSIS TARGETING CHIMERA COMPOUND AND USE THEREOF 甘李药业股份有限公司 2024-08-02 — — WO disclosed
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