Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31027433 | 1.00 | SCN7A (0.39) | SCN7ASCN5ASCN2ASCN8ACYP2A6 | |
| SCHEMBL30406507 | 0.83 | MEN1 (0.37) | SCN7ASCN5ASCN2ASCN8ACYP2A6 | |
| SCHEMBL31027384 | 0.70 | MEN1 (0.39) | HRH2HRH1HRH3MEN1ALDH1A1 | |
| SCHEMBL24993899 | 0.62 | KMO (0.61) | — | |
| SCHEMBL31271107 | 0.61 | KDM4E (0.47) | ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL1663338 | 0.60 | SIGMAR1 (0.59) | HRH3MEN1ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL19687586 | 0.60 | MEN1 (0.46) | MEN1ALDH1A1GAAHPGDKDM4E | |
| SCHEMBL31611878 | 0.60 | HTR3E (0.63) | SMN1; SMN2ALDH1A1SLC6A4KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL28629993 | 0.59 | CXCR4 (0.60) | HRH3MEN1KMT2ASIGMAR1 | |
| SCHEMBL19687594 | 0.59 | ESR1 (0.40) | SCN7ASCN5ASCN2ASCN8AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647378-A | Inhibitors of Mei Nen protein interaction with MLL | 巴拉疗法公司 | 2024-09-13 | — | — | CN | disclosed |