Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD1 | O95696 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 2/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30200885 | 1.00 | CA1 (0.49) | CA1CA2BRD4BRD1BRPF1 | |
| SCHEMBL264948 | 0.83 | EDNRB (0.45) | CA1CA2FLT1FLT4KDR | |
| SCHEMBL9474855 | 0.83 | CA1 (0.51) | CA1CA2BRD4BRD1BRPF1 | |
| SCHEMBL31195820 | 0.81 | L3MBTL1 (0.59) | CA1CA2BRD4BRD1BRPF1 | |
| SCHEMBL2333956 | 0.81 | L3MBTL1 (0.59) | CA1CA2BRD4BRD1BRPF1 | |
| SCHEMBL3351008 | 0.79 | PDIA6 (0.51) | CA1CA2BRD4BRD1BRPF1 | |
| SCHEMBL30200838 | 0.79 | PDIA6 (0.51) | CA1CA2BRD4BRD1BRPF1 | |
| SCHEMBL6012134 | 0.79 | CA1 (0.49) | CA1CA2BRD4BRD1BRPF1 | |
| SCHEMBL31470482 | 0.78 | HSP90AA1 (0.43) | CA1CA2TRPV4FLT1FLT4 | |
| SCHEMBL1814581 | 0.78 | HSP90AA1 (0.43) | CA1CA2TRPV4FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199826-A | Pressure-bearing control temporary plugging agent based on melting method and preparation method thereof | 中海石油(中国)有限公司 | 2023-06-02 | — | — | CN | claimed |
| US-12565497-B2 | Sulfone derivatives | HOFFMANN-LA ROCHE INC. (US) | 2026-03-03 | — | — | US | disclosed |
| US-20250270194-A1 | PYRAZOLE-SUBSTITUTED CYCLOPENTANOL ESTER DERIVATIVE AND USE THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2025-08-28 | — | — | US | disclosed |
| EP-4580621-A2 | T-TYPE VOLTAGE-GATED CALCIUM CHANNEL POTENTIATORS | The Broad Institute, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| US-20250197387-A1 | BCL-XL DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-06-19 | — | — | US | disclosed |
| CN-120091815-A | T-type voltage-gated calcium channel enhancer | 广泛研究所股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-119977905-A | Green synthesis method of saccharin and saccharin derivative | 湖南科技大学 | 2025-05-13 | — | — | CN | disclosed |
| US-20250084067-A1 | PYRAZOLE-SUBSTITUTED CYCLOPENTANOL ESTER DERIVATIVE AND USE THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2025-03-13 | — | — | US | disclosed |
| EP-4516786-A1 | PYRAZOLE-SUBSTITUTED CYCLOPENTANOL ESTER DERIVATIVE AND USE THEREOF | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2025-03-05 | — | — | EP | disclosed |
| CN-119384413-A | Anilino-pyrazole derivatives, compositions and methods thereof | 昂胜医药有限公司 | 2025-01-28 | — | — | CN | disclosed |
| US-6166005-A | Heterocyclic metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY | 2000-12-26 | — | — | US | disclosed |
| CN-1228773-A | Heterocyclic metalloprotease inhibitors | PROCTER & GAMBLE (US) | 1999-09-15 | — | — | CN | disclosed |
| EP-0927161-A1 | SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| EP-0925287-A1 | HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998008815-A1 | SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1998008827-A1 | HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| US-4804673-A | Fungicidal sulfonyl azoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-02-14 | — | — | US | disclosed |
| US-4710509-A | IMIDAZOLE AND TRIAZOLE DERIVATIVES; FUNGICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1987-12-01 | — | — | US | disclosed |
| EP-0237912-A1 | Sulfonyl azoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0173918-A2 | Substituted phenylsulfonyl azoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084067-A1 | PYRAZOLE-SUBSTITUTED CYCLOPENTANOL ESTER DERIVATIVE AND USE THEREOF | CYP51A1, CYP11B2, CYP11B1 | CA1 1702/4885CA2 2046/4885BRD4 1875/4885 |
| US-20250197387-A1 | BCL-XL DEGRADERS AND USES THEREOF | XIAP, BCL2L1, BCL2L10 | CA1 2550/4885CA2 3825/4885BRD4 303/4885 |
| US-20250270194-A1 | PYRAZOLE-SUBSTITUTED CYCLOPENTANOL ESTER DERIVATIVE AND USE THEREOF | CYP51A1, CYP11B2, CYP11B1 | CA1 1702/4885CA2 2046/4885BRD4 1875/4885 |
| US-12565497-B2 | Sulfone derivatives | CXCR1, CCR1, SULT1E1 | CA1 406/4885CA2 236/4885BRD4 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.