SCHEMBL31470482

SCHEMBL31470482

O=S(=O)(Cl)c1ccc(Br)cc1Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.43
TLR9 Q9NR96 1/20 0.43
ALOX15 P16050 1/20 0.39
CA2 P00918 5/20 0.38
S100A4 P26447 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TRPV4 Q9HBA0 3/20 0.37
CA9 Q16790 3/20 0.36
CA1 P00915 3/20 0.36
CA12 O43570 2/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
FLT1 P17948 1/20 0.36
FLT4 P35916 1/20 0.36
KDR P35968 1/20 0.36
GLA P06280 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1814581 1.00 HSP90AA1 (0.43) HSP90AA1TLR9ALOX15CA2S100A4
SCHEMBL198775 0.82 LMNA (0.44) HSP90AA1TLR9CA2S100A4ALDH1A1
SCHEMBL29882666 0.82 LMNA (0.44) HSP90AA1TLR9CA2S100A4ALDH1A1
SCHEMBL16507 0.80 TRPV4 (0.53) CA2S100A4ALDH1A1MAPK1TRPV4
SCHEMBL4142707 0.80 TSHR (0.54) CA2S100A4ALDH1A1MAPK1TRPV4
SCHEMBL31450141 0.80 TSHR (0.54) CA2S100A4ALDH1A1MAPK1TRPV4
SCHEMBL310277 0.78 CA1 (0.49) CA2S100A4L3MBTL1TRPV4CA1
SCHEMBL121016 0.78 AKR1B1 (0.49) ALOX15S100A4ALDH1A1TRPV4TSHR
SCHEMBL20889223 0.78 BCL2 (0.42) ALOX15CA2S100A4TRPV4CA9
SCHEMBL9997269 0.78 TRPV4 (0.35) CA2TRPV4CA1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119565410-A Seawater desalination reverse osmosis membrane, preparation method and application 湖南澳维膜科技有限公司 2025-03-07 CN claimed
CN-119565410-A Seawater desalination reverse osmosis membrane, preparation method and application 湖南澳维膜科技有限公司 2025-03-07 CN disclosed