Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 8/20 | 0.40 |
| ▸ | CA4 | P22748 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 3/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028756 | 0.80 | CA2 (0.47) | PTGS2SOS1APLNRCA2CA4 | |
| SCHEMBL31028734 | 0.80 | APLNR (0.42) | PTGS2SOS1APLNRCA2CA4 | |
| SCHEMBL1700090 | 0.78 | CA2 (0.48) | PTGS2APLNRCA2CA4CA1 | |
| SCHEMBL5626144 | 0.78 | NOS3 (0.52) | PTGS2APLNRCA2CA4CA1 | |
| SCHEMBL31028738 | 0.78 | KDM4E (0.40) | PTGS2APLNRCA2CA4PTGS1 | |
| SCHEMBL31028653 | 0.77 | CA2 (0.50) | PTGS2SOS1APLNRCA2CA4 | |
| SCHEMBL31028737 | 0.77 | ALDH1A1 (0.41) | PTGS2APLNRCA2CA4PTGS1 | |
| SCHEMBL31028676 | 0.77 | PTGS2 (0.45) | PTGS2SOS1APLNRCA2CA4 | |
| SCHEMBL1207411 | 0.77 | ALDH1A1 (0.41) | PTGS2APLNRCA2CA4PTGS1 | |
| SCHEMBL13826164 | 0.70 | CA2 (0.46) | PTGS2APLNRCA2CA4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | disclosed |