Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25246669 | 1.00 | BAZ2B (0.40) | BAZ2BL3MBTL1NLRP3ALDH1A1GSTO1 | |
| SCHEMBL20635980 | 0.81 | BAZ2B (0.40) | BAZ2BNLRP3ALDH1A1NPC1RAB9A | |
| SCHEMBL6866811 | 0.79 | NLRP3 (0.57) | BAZ2BNLRP3ALDH1A1SMN1; SMN2ATM | |
| SCHEMBL22013712 | 0.76 | NLRP3 (0.54) | BAZ2BNLRP3ALDH1A1SMN1; SMN2ATM | |
| SCHEMBL20194506 | 0.75 | NLRP3 (0.53) | NLRP3ALDH1A1SMN1; SMN2ATM | |
| SCHEMBL30416876 | 0.73 | HDAC1 (0.44) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25237122 | 0.73 | HDAC1 (0.44) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23063205 | 0.73 | KDM4E (0.40) | BAZ2BL3MBTL1NLRP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL6842000 | 0.73 | MAPT (0.43) | NLRP3ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25082660 | 0.72 | ALDH1A1 (0.43) | BAZ2BALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109126-A1 | DIHYDRO-OXAZOL DERIVATIVE COMPOUNDS | AC IMMUNE SA (CH) | 2025-04-03 | — | — | US | disclosed |
| CN-118541366-A | Dihydrooxazole derivative compound | AC免疫有限公司 | 2024-08-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250109126-A1 | DIHYDRO-OXAZOL DERIVATIVE COMPOUNDS | NLRP3, NLRP1, NOD1 | BAZ2B 580/4885L3MBTL1 2214/4885NLRP3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.