Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031221 | 1.00 | HTR3E (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20515380 | 0.90 | IKBKB (0.40) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL18838764 | 0.90 | IKBKB (0.40) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL31031228 | 0.85 | ALDH1A1 (0.32) | ALDH1A1KDM4ETP53RAB9APIK3CA | |
| SCHEMBL31031231 | 0.85 | KDM4E (0.32) | ALDH1A1KDM4EGLAGAA | |
| SCHEMBL31031244 | 0.84 | KCNH2 (0.34) | — | |
| SCHEMBL31031220 | 0.81 | — | — | |
| SCHEMBL31031224 | 0.81 | KDM4E (0.40) | ALDH1A1KDM4EGLAGAA | |
| SCHEMBL31031256 | 0.80 | KDM4E (0.37) | ALDH1A1KDM4EGLAGAA | |
| SCHEMBL31031252 | 0.79 | LRRK2 (0.48) | PIK3CAPIK3CBPIK3CGGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |