Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031241 | 0.89 | KDM4E (0.37) | KDM4EALDH1A1GLAGAACSNK2A2 | |
| SCHEMBL31031224 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1GLAGAACSNK2A2 | |
| SCHEMBL31031235 | 0.83 | KDM4E (0.33) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL31031221 | 0.80 | HTR3E (0.40) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL31031217 | 0.80 | HTR3E (0.40) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL31031231 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL31031228 | 0.78 | ALDH1A1 (0.32) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL31031244 | 0.77 | KCNH2 (0.34) | — | |
| SCHEMBL31031220 | 0.75 | — | — | |
| SCHEMBL20515380 | 0.73 | IKBKB (0.40) | KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |