Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 13/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031232 | 0.88 | KCNH2 (0.34) | KCNH2HRH4HRH3TRPC5TRPC4 | |
| SCHEMBL31031221 | 0.84 | HTR3E (0.40) | — | |
| SCHEMBL31031217 | 0.84 | HTR3E (0.40) | — | |
| SCHEMBL31031228 | 0.81 | ALDH1A1 (0.32) | — | |
| SCHEMBL31031231 | 0.81 | KDM4E (0.32) | — | |
| SCHEMBL31031261 | 0.80 | — | — | |
| SCHEMBL31031220 | 0.79 | — | — | |
| SCHEMBL31031224 | 0.79 | KDM4E (0.40) | — | |
| SCHEMBL31031256 | 0.77 | KDM4E (0.37) | — | |
| SCHEMBL20515380 | 0.77 | IKBKB (0.40) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |