Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6143783 | 0.87 | ACHE (0.56) | KDM4EALDH1A1TP53HRH3DRD2 | |
| SCHEMBL31033146 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TP53HRH3DRD2DRD3 | |
| SCHEMBL30024414 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1POLBACHEMAPT | |
| SCHEMBL3653396 | 0.74 | HRH3 (0.69) | HRH3DRD2DRD3GRM5 | |
| SCHEMBL31033165 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TP53HRH3DRD2DRD3 | |
| SCHEMBL12160564 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1POLBACHEMAPT | |
| SCHEMBL31033174 | 0.72 | PRMT5 (0.49) | ALDH1A1TP53HRH3DRD2DRD3 | |
| SCHEMBL8406066 | 0.71 | HTR1A (0.52) | KDM4EALDH1A1POLB | |
| SCHEMBL613873 | 0.71 | HTR2A (0.43) | ALDH1A1DRD2POLB | |
| SCHEMBL13242218 | 0.71 | ALDH1A1 (0.47) | KDM4EALDH1A1TP53HRH3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163956-A2 | SIGMA RECEPTOR LIGAND COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-08 | — | — | WO | disclosed |