Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653396 | 0.79 | HRH3 (0.69) | HRH3HTR2AHTR7DRD2DRD3 | |
| SCHEMBL6144233 | 0.78 | ALDH1A1 (0.49) | HRH3ALDH1A1TP53PARP1DRD2 | |
| SCHEMBL29802804 | 0.73 | DRD3 (0.67) | PARP1HTR7DRD2DRD3 | |
| SCHEMBL29097638 | 0.70 | ALDH1A1 (0.69) | ALDH1A1TP53 | |
| SCHEMBL3243125 | 0.70 | ALDH1A1 (0.69) | ALDH1A1TP53 | |
| SCHEMBL6143783 | 0.69 | ACHE (0.56) | HRH3ALDH1A1TP53DRD2DRD3 | |
| SCHEMBL31033174 | 0.69 | PRMT5 (0.49) | HRH3ALDH1A1TP53DRD2DRD3 | |
| SCHEMBL31033159 | 0.69 | KDM4E (0.48) | HRH3ALDH1A1TP53DRD2DRD3 | |
| SCHEMBL31033190 | 0.69 | ALDH1A1 (0.51) | ALDH1A1TP53HTR7DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL27677246 | 0.68 | ALDH1A1 (0.67) | ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163956-A2 | SIGMA RECEPTOR LIGAND COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-08 | — | — | WO | disclosed |