Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175693 | 0.79 | ELANE (0.35) | — | |
| SCHEMBL8980633 | 0.79 | HEXA (0.38) | ALDH1A1MAPTPARP1MEN1RAB9A | |
| SCHEMBL31033169 | 0.78 | HRH3 (0.49) | ALDH1A1TP53DRD2DRD3HRH3 | |
| Hydrochloric Acid SCHEMBL11074171 | 0.78 | KDM1A (0.44) | ALDH1A1TP53DRD2DRD3HRH3 | |
| SCHEMBL3653396 | 0.72 | HRH3 (0.69) | DRD2DRD3HRH3GRM5 | |
| SCHEMBL3243125 | 0.72 | ALDH1A1 (0.69) | ALDH1A1TP53MAPTTERTMEN1 | |
| SCHEMBL29097638 | 0.72 | ALDH1A1 (0.69) | ALDH1A1TP53MAPTTERTMEN1 | |
| SCHEMBL6143783 | 0.71 | ACHE (0.56) | ALDH1A1TP53DRD2DRD3HRH3 | |
| SCHEMBL9166362 | 0.71 | MMP2 (0.34) | ALDH1A1MAPTRAB9A | |
| SCHEMBL31033159 | 0.70 | KDM4E (0.48) | ALDH1A1TP53DRD2DRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534690-A1 | 2-SUBSTITUTED BICYCLIC BENZOHETEROCYCLIC COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | Euro-Celtique S.A. (LU) | 2005-06-01 | — | — | EP | disclosed |
| US-20040152696-A1 | 2-substituted bicyclic benzoheterocyclic compounds and their use as sodium channel blockers | EURO-CELTIQUE S.A. | 2004-08-05 | — | — | US | disclosed |
| WO-2004013111-A1 | 2-SUBSTITUTED BICYCLIC BENZOHETEROCYCLIC COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152696-A1 | 2-substituted bicyclic benzoheterocyclic compounds and their use as sodium channel blockers | CACNA1C, CACNA1D, SCN2B | ALDH1A1 803/4885TP53 3877/4885DRD2 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.