7-Hydroxyflavone

7-Hydroxyflavone

SCHEMBL31035954

Cl[Mn]Cl.O=c1cc(-c2ccccc2)oc2cc(O)ccc12.O=c1cc(-c2ccccc2)oc2cc(O)ccc12

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 6/20 0.89
▸ MAOB P27338 3/20 0.89
▸ MAOA P21397 2/20 0.89
▸ CALM1 P0DP23 2/20 0.89
▸ PKM P14618 2/20 0.89
▸ FTO Q9C0B1 2/20 0.89
▸ CA12 O43570 2/20 0.89
▸ CA1 P00915 2/20 0.89
▸ CA2 P00918 2/20 0.89
▸ ABCB1 P08183 2/20 0.89
▸ CYP1B1 Q16678 2/20 0.89
▸ CA9 Q16790 2/20 0.89
▸ AKR1B10 O60218 1/20 0.89
▸ CYP1A2 P05177 1/20 0.89
▸ HSD17B1 P14061 1/20 0.89
▸ AKR1B1 P15121 1/20 0.89
▸ HSD17B3 P37058 1/20 0.89
▸ XDH P47989 1/20 0.89
▸ HPGD P15428 5/20 0.73
▸ SMN1; SMN2 Q16637 5/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7-Hydroxyflavone SCHEMBL312148 0.94 CYP19A1 (1.00) CYP19A1MAOBMAOACALM1PKM
7-Hydroxyflavone SCHEMBL29678183 0.94 CYP19A1 (1.00) CYP19A1MAOBMAOACALM1PKM
7-Hydroxyflavone SCHEMBL27789687 0.93 CYP19A1 (0.97) CYP19A1MAOBMAOACALM1PKM
7-Hydroxyflavone SCHEMBL10808394 0.93 CYP19A1 (0.97) CYP19A1MAOBMAOACALM1PKM
7-Hydroxyflavone SCHEMBL27889515 0.89 CYP19A1 (0.89) CYP19A1MAOBMAOACALM1PKM
Flavone SCHEMBL3515129 0.87 CYP19A1 (0.86) CYP19A1MAOBMAOACALM1PKM
SCHEMBL157723 0.85 CYP3A4 (1.00) CYP19A1MAOBMAOACALM1PKM
SCHEMBL31167385 0.85 CYP3A4 (1.00) CYP19A1MAOBMAOACALM1PKM
SCHEMBL31675776 0.84 CYP3A4 (1.00) CYP19A1MAOBMAOACALM1PKM
SCHEMBL3135989 0.84 CYP3A4 (1.00) CYP19A1MAOBMAOACALM1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071179-A1 PRODUCTION METHOD OF NERVE CELLS DAMAGED BY OXIDATIVE STRESS AND APPLICATIONS THEREOF FUJIFILM CORPORATION (JP) 2026-03-12 — — US disclosed
EP-4682249-A1 METHOD FOR PRODUCING NERVE CELLS DAMAGED BY OXIDATION STRESS AND APPLICATION THEREOF FUJIFILM Corporation (JP) 2026-01-21 — — EP disclosed
WO-2024190850-A1 METHOD FOR PRODUCING NERVE CELLS DAMAGED BY OXIDATION STRESS AND APPLICATION THEREOF 富士フイルム株式会社 2024-09-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071179-A1 PRODUCTION METHOD OF NERVE CELLS DAMAGED BY OXIDATIVE STRESS AND APPLICATIONS THEREOF AIFM2, AIFM1, FECH CYP19A1 4745/4885MAOB 1273/4885MAOA 1645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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