SCHEMBL31037301

SCHEMBL31037301

O=C(NCCc1cccnc1)Nc1ccc(CC(=O)N2CCCCC2)c(C#Cc2ccc(F)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAMPT P43490 12/20 0.50
▸ PRMT3 O60678 4/20 0.42
▸ LMNA P02545 1/20 0.41
▸ C3AR1 Q16581 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037443 0.91 NAMPT (0.43) NAMPTPRMT3LMNAC3AR1
SCHEMBL31037293 0.81 LMNA (0.48) NAMPTPRMT3LMNANPC1MAPT
SCHEMBL31037286 0.81 LMNA (0.48) NAMPTPRMT3LMNANPC1MAPT
SCHEMBL31037254 0.80 NAMPT (0.46) NAMPTPRMT3LMNANPC1MAPT
SCHEMBL31037302 0.79 NAMPT (0.51) NAMPTPRMT3LMNANPC1MAPT
SCHEMBL31037328 0.78 NAMPT (0.46) NAMPTPRMT3LMNARAB9A
SCHEMBL31037483 0.78 NAMPT (0.47) NAMPTPRMT3LMNA
SCHEMBL31037498 0.78 LMNA (0.44) NAMPTPRMT3LMNARAB9A
SCHEMBL31037335 0.77 KEAP1 (0.44) NAMPTPRMT3LMNA
SCHEMBL31037357 0.75 PAX8 (0.42) NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663628-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Samjin Pharmaceutical Co., Ltd. (KR) 2025-12-17 — — EP disclosed
WO-2024166024-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2024-08-15 — — WO disclosed
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