Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31044923 | 0.93 | CRHR1 (0.37) | PDE4BPIK3CDPIK3R1NPC1GALR3 | |
| SCHEMBL31044664 | 0.90 | NPC1 (0.37) | PDE4BPIK3CDPIK3R1NPC1GALR3 | |
| SCHEMBL31044932 | 0.89 | NPC1 (0.39) | PIK3CDPIK3R1NPC1GALR3NR2F2 | |
| SCHEMBL31045030 | 0.88 | NPC1 (0.35) | NPC1GALR3NR2F2RAB9ASTK17A | |
| SCHEMBL31044958 | 0.87 | NPC1 (0.36) | PDE4BPIK3CDPIK3R1NPC1GALR3 | |
| SCHEMBL31044889 | 0.85 | NPC1 (0.35) | PDE4BPIK3CDPIK3R1NPC1GALR3 | |
| SCHEMBL31044704 | 0.83 | TRIM58 (0.40) | NPC1GALR3NR2F2RAB9A | |
| SCHEMBL31045439 | 0.83 | NPC1 (0.40) | NPC1GALR3NR2F2RAB9AMAPT | |
| SCHEMBL31044754 | 0.83 | RAB9A (0.44) | NPC1GALR3NR2F2RAB9AMAPT | |
| SCHEMBL31044903 | 0.82 | PRKCI (0.44) | NPC1GALR3NR2F2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | FIMBRION THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | G6PD, SDHA, NQO1 | PDE4B 1084/4885PIK3CD 2267/4885PIK3R1 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.